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Source: Romanian Journal of Morphology and Embryology

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Total 4752 results found since Jan 2013.

In vitro evaluation of Axitinib and Sorafenib treatment in glioblastoma cell viability and morphology
Rom J Morphol Embryol. 2023 Apr-Jun;64(2):173-180. doi: 10.47162/RJME.64.2.07.ABSTRACTThe formation, proliferation, and evolution of glioblastoma (GB) are significantly influenced by pathological angiogenesis. This is supported by several growth factor receptors, such as the vascular endothelial growth factor receptor (VEGFR). In this experiment, we examined how the Food and Drug Administration (FDA) approved VEGFR blockers Sorafenib and Axitinib affect the viability of GB cells in vitro. Cells were cultivated in 96-well culture plates for the experiments, afterwards Sorafenib and Axitinib were administered at doses rangin...
Source: Romanian Journal of Morphology and Embryology - July 30, 2023 Category: General Medicine Authors: Alexandru Opri ţa Mihaela Amelia Dobrescu Elena Victoria Manea Ştefana Oana Popescu Ani Simona Sevastre Andreea Silvia P îrvu Iuliana Mihaela Buzatu Daniela Elise Tache Source Type: research

Epidemiological and pathological characteristics of spinal metastases from gastrointestinal cancers - a series of 40 cases
Rom J Morphol Embryol. 2023 Apr-Jun;64(2):225-234. doi: 10.47162/RJME.64.2.13.ABSTRACTSpinal metastases from gastrointestinal (GI) cancer are rare and as a result there are only case reports or small series in the literature. The aim of our work was to identify the demographic aspects, the location, and the histopathological aspects of spinal metastases from GI cancers diagnosed and treated in a reference Hospital in Romania over a period of nine years, and comparing the data obtained with those from the recent literature. This is a retrospective case series study on spinal metastases from GI cancers, developed in patients...
Source: Romanian Journal of Morphology and Embryology - July 30, 2023 Category: General Medicine Authors: Ştefan Şelaru Anca Sava Drago ş Viorel Scripcariu Claudia Florida Costea Ana Maria Dumitrescu Bogdan Cost ăchescu Gabriela Floren ţa Dumitrescu Corina Ciupilan Ruxandra Vatavu Raluca Maria Haba Vladimir Poroch Lucia Corina Dima-Cozma Valeriana Vornic Source Type: research

Effects of Coriandrum sativum on distant organ inflammation and apoptosis due to liver ischemia/reperfusion injury
In conclusion, it was observed that liver IR caused changes in distant organs, especially in the small intestine, lung, and kidneys. Damaging effects of IR as well as apoptosis and inflammation were found to be decreased in the groups treated with CS.PMID:37518878 | DOI:10.47162/RJME.64.2.11
Source: Romanian Journal of Morphology and Embryology - July 30, 2023 Category: General Medicine Authors: Aysel K ükner Pelin Toros Gizem S öyler Selin Isik G özde Ögütçü Oguzhan Edebal Filiz Meri çli Source Type: research

In vitro evaluation of Axitinib and Sorafenib treatment in glioblastoma cell viability and morphology
Rom J Morphol Embryol. 2023 Apr-Jun;64(2):173-180. doi: 10.47162/RJME.64.2.07.ABSTRACTThe formation, proliferation, and evolution of glioblastoma (GB) are significantly influenced by pathological angiogenesis. This is supported by several growth factor receptors, such as the vascular endothelial growth factor receptor (VEGFR). In this experiment, we examined how the Food and Drug Administration (FDA) approved VEGFR blockers Sorafenib and Axitinib affect the viability of GB cells in vitro. Cells were cultivated in 96-well culture plates for the experiments, afterwards Sorafenib and Axitinib were administered at doses rangin...
Source: Romanian Journal of Morphology and Embryology - July 30, 2023 Category: General Medicine Authors: Alexandru Opri ţa Mihaela Amelia Dobrescu Elena Victoria Manea Ştefana Oana Popescu Ani Simona Sevastre Andreea Silvia P îrvu Iuliana Mihaela Buzatu Daniela Elise Tache Source Type: research

Epidemiological and pathological characteristics of spinal metastases from gastrointestinal cancers - a series of 40 cases
Rom J Morphol Embryol. 2023 Apr-Jun;64(2):225-234. doi: 10.47162/RJME.64.2.13.ABSTRACTSpinal metastases from gastrointestinal (GI) cancer are rare and as a result there are only case reports or small series in the literature. The aim of our work was to identify the demographic aspects, the location, and the histopathological aspects of spinal metastases from GI cancers diagnosed and treated in a reference Hospital in Romania over a period of nine years, and comparing the data obtained with those from the recent literature. This is a retrospective case series study on spinal metastases from GI cancers, developed in patients...
Source: Romanian Journal of Morphology and Embryology - July 30, 2023 Category: General Medicine Authors: Ştefan Şelaru Anca Sava Drago ş Viorel Scripcariu Claudia Florida Costea Ana Maria Dumitrescu Bogdan Cost ăchescu Gabriela Floren ţa Dumitrescu Corina Ciupilan Ruxandra Vatavu Raluca Maria Haba Vladimir Poroch Lucia Corina Dima-Cozma Valeriana Vornic Source Type: research

Effects of Coriandrum sativum on distant organ inflammation and apoptosis due to liver ischemia/reperfusion injury
In conclusion, it was observed that liver IR caused changes in distant organs, especially in the small intestine, lung, and kidneys. Damaging effects of IR as well as apoptosis and inflammation were found to be decreased in the groups treated with CS.PMID:37518878 | DOI:10.47162/RJME.64.2.11
Source: Romanian Journal of Morphology and Embryology - July 30, 2023 Category: General Medicine Authors: Aysel K ükner Pelin Toros Gizem S öyler Selin Isik G özde Ögütçü Oguzhan Edebal Filiz Meri çli Source Type: research

In vitro evaluation of Axitinib and Sorafenib treatment in glioblastoma cell viability and morphology
Rom J Morphol Embryol. 2023 Apr-Jun;64(2):173-180. doi: 10.47162/RJME.64.2.07.ABSTRACTThe formation, proliferation, and evolution of glioblastoma (GB) are significantly influenced by pathological angiogenesis. This is supported by several growth factor receptors, such as the vascular endothelial growth factor receptor (VEGFR). In this experiment, we examined how the Food and Drug Administration (FDA) approved VEGFR blockers Sorafenib and Axitinib affect the viability of GB cells in vitro. Cells were cultivated in 96-well culture plates for the experiments, afterwards Sorafenib and Axitinib were administered at doses rangin...
Source: Romanian Journal of Morphology and Embryology - July 30, 2023 Category: General Medicine Authors: Alexandru Opri ţa Mihaela Amelia Dobrescu Elena Victoria Manea Ştefana Oana Popescu Ani Simona Sevastre Andreea Silvia P îrvu Iuliana Mihaela Buzatu Daniela Elise Tache Source Type: research

Epidemiological and pathological characteristics of spinal metastases from gastrointestinal cancers - a series of 40 cases
Rom J Morphol Embryol. 2023 Apr-Jun;64(2):225-234. doi: 10.47162/RJME.64.2.13.ABSTRACTSpinal metastases from gastrointestinal (GI) cancer are rare and as a result there are only case reports or small series in the literature. The aim of our work was to identify the demographic aspects, the location, and the histopathological aspects of spinal metastases from GI cancers diagnosed and treated in a reference Hospital in Romania over a period of nine years, and comparing the data obtained with those from the recent literature. This is a retrospective case series study on spinal metastases from GI cancers, developed in patients...
Source: Romanian Journal of Morphology and Embryology - July 30, 2023 Category: General Medicine Authors: Ştefan Şelaru Anca Sava Drago ş Viorel Scripcariu Claudia Florida Costea Ana Maria Dumitrescu Bogdan Cost ăchescu Gabriela Floren ţa Dumitrescu Corina Ciupilan Ruxandra Vatavu Raluca Maria Haba Vladimir Poroch Lucia Corina Dima-Cozma Valeriana Vornic Source Type: research

Effects of Coriandrum sativum on distant organ inflammation and apoptosis due to liver ischemia/reperfusion injury
In conclusion, it was observed that liver IR caused changes in distant organs, especially in the small intestine, lung, and kidneys. Damaging effects of IR as well as apoptosis and inflammation were found to be decreased in the groups treated with CS.PMID:37518878 | DOI:10.47162/RJME.64.2.11
Source: Romanian Journal of Morphology and Embryology - July 30, 2023 Category: General Medicine Authors: Aysel K ükner Pelin Toros Gizem S öyler Selin Isik G özde Ögütçü Oguzhan Edebal Filiz Meri çli Source Type: research

In vitro evaluation of Axitinib and Sorafenib treatment in glioblastoma cell viability and morphology
Rom J Morphol Embryol. 2023 Apr-Jun;64(2):173-180. doi: 10.47162/RJME.64.2.07.ABSTRACTThe formation, proliferation, and evolution of glioblastoma (GB) are significantly influenced by pathological angiogenesis. This is supported by several growth factor receptors, such as the vascular endothelial growth factor receptor (VEGFR). In this experiment, we examined how the Food and Drug Administration (FDA) approved VEGFR blockers Sorafenib and Axitinib affect the viability of GB cells in vitro. Cells were cultivated in 96-well culture plates for the experiments, afterwards Sorafenib and Axitinib were administered at doses rangin...
Source: Romanian Journal of Morphology and Embryology - July 30, 2023 Category: General Medicine Authors: Alexandru Opri ţa Mihaela Amelia Dobrescu Elena Victoria Manea Ştefana Oana Popescu Ani Simona Sevastre Andreea Silvia P îrvu Iuliana Mihaela Buzatu Daniela Elise Tache Source Type: research

Epidemiological and pathological characteristics of spinal metastases from gastrointestinal cancers - a series of 40 cases
Rom J Morphol Embryol. 2023 Apr-Jun;64(2):225-234. doi: 10.47162/RJME.64.2.13.ABSTRACTSpinal metastases from gastrointestinal (GI) cancer are rare and as a result there are only case reports or small series in the literature. The aim of our work was to identify the demographic aspects, the location, and the histopathological aspects of spinal metastases from GI cancers diagnosed and treated in a reference Hospital in Romania over a period of nine years, and comparing the data obtained with those from the recent literature. This is a retrospective case series study on spinal metastases from GI cancers, developed in patients...
Source: Romanian Journal of Morphology and Embryology - July 30, 2023 Category: General Medicine Authors: Ştefan Şelaru Anca Sava Drago ş Viorel Scripcariu Claudia Florida Costea Ana Maria Dumitrescu Bogdan Cost ăchescu Gabriela Floren ţa Dumitrescu Corina Ciupilan Ruxandra Vatavu Raluca Maria Haba Vladimir Poroch Lucia Corina Dima-Cozma Valeriana Vornic Source Type: research

Effects of Coriandrum sativum on distant organ inflammation and apoptosis due to liver ischemia/reperfusion injury
In conclusion, it was observed that liver IR caused changes in distant organs, especially in the small intestine, lung, and kidneys. Damaging effects of IR as well as apoptosis and inflammation were found to be decreased in the groups treated with CS.PMID:37518878 | DOI:10.47162/RJME.64.2.11
Source: Romanian Journal of Morphology and Embryology - July 30, 2023 Category: General Medicine Authors: Aysel K ükner Pelin Toros Gizem S öyler Selin Isik G özde Ögütçü Oguzhan Edebal Filiz Meri çli Source Type: research